Avoid drinking alcohol, which can increase some of the side effects of promethazine. Promethazine with Codeine contains an opioid (narcotic) cough medicine, and may be habit-forming. Promethazine doses are based on weight in children, and any changes may affect your child's dose. Take promethazine exactly as prescribed by your doctor. Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. Avoid analeptics, which may cause convulsions. The 50 mg also contains D&C Red # 27 Lake. and untreated or inadequately treated extrapyramidal signs and symptoms (EPS). These doses are from approximately 2.1 to 4.2 times the maximum recommended total daily dose of promethazine for a 50-kg subject, depending upon the indication for which the drug is prescribed. Promethazine Description. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Generic name: promethazine (oral) [pro-METH-a-zeen] Dosage must be individualized. 2021 Par Pharmaceutical. Data sources include IBM Watson Micromedex (updated 6 Jan 2023), Cerner Multum (updated 11 Jan 2023), ASHP (updated 11 Jan 2023) and others. Promethazine and dextromethorphan should be given to a pregnant woman only if clearly needed. The average oral dose is 25 mg taken before retiring; however, 12.5 mg may be taken before meals and on retiring, if necessary. Your doctor may occasionally change your dose to make sure you get the best results. Dry ice blasting is considered to be an environmentally-friendly method of cleaning. ANTIEMETICS ARE NOT RECOMMENDED FOR TREATMENT OF UNCOMPLICATED VOMITING IN PEDIATRIC PATIENTS, AND THEIR USE SHOULD BE LIMITED TO PROLONGED VOMITING OF KNOWN ETIOLOGY. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use promethazine only for the indication prescribed. Promethazine should be used with caution in patients with bone marrow depression. Promethazine Tablets. Neuroleptic Malignant Syndrome Avoid analeptics which may cause convulsions. Dispense in a tight, light-resistant container with a child-resistant closure as defined in the USP. Promethazine hydrochloride and dextromethorphan hydrobromide oral solution is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. You should not breast-feed while using this medicine. PAR promethazine with codeine is a purple syrup and Hi-Tech promethazine with codeine is a red syrup. Dextromethorphan should not be used in patients receiving a monoamine oxidase inhibitor (MAOI) (see PRECAUTIONS, Drug Interactions). Promethazine hydrochloride and dextromethorphan hydrobromide oral solution is contraindicated for children under 2 years of age (see WARNINGS Black Box Warning and Use In Pediatric Patients). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Promethazine Hydrochloride Tablets USP, 50 mg are pink color, biconvex, round tablets, debossed with AN above 522 on one side and plain on the other side are supplied as: Bottles of 100: NDC 53746-522-01. EPINEPHRINE SHOULD NOT BE USED, since its use in patients with partial adrenergic blockade may further lower the blood pressure. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PROMETHAZINE HYDROCHLORIDE TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER. Pregnancy Tests: Diagnostic pregnancy tests based on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations. To report SUSPECTED ADVERSE REACTIONS, contact Amneal Pharmaceuticals at 1-877-835-5472 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. . It has several uses. Promethazine hydrochloride tablets should be used with caution in pediatric patients 2 years of age and older (see WARNINGS: Use in Pediatric Patients). Promethazine and dextromethorphan should be used during pregnancy only if the potential benefit justifies the risk to the fetus. Dosage form: tablet Clinical studies of promethazine hydrochloride and dextromethorphan hydrobromide oral solution did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Since reoccurrences of NMS have been reported with phenothiazines, the reintroduction of promethazine hydrochloride should be carefully considered. Promethazine administered to a pregnant woman within two weeks of delivery may inhibit platelet aggregation in the newborn. They both contain the same dose of active ingredients promethazine hydrochloride/codeine phosphate 6.25mg-10mg/5mL syrup. Pharmaceutical. Limited experience with dialysis indicates that it is not helpful. Tell your doctor about all the prescription and over-the-counter medications you use. Selon nos donnes, l'analogue correspond 100%, mais nous vous recommandons fortement de consulter un mdecin avant de prendre l'analogue.. Dry ice blasting is a new and environmentally safe way to clean industrial equipment and outside/indoor surfaces that are exposed to the elements. Generic name: promethazine hydrochloride Available for Android and iOS devices. THE USE OF PROMETHAZINE PRODUCTS SHOULD BE AVOIDED IN PEDIATRIC PATIENTS WHOSE SIGNS AND SYMPTOMS MAY SUGGEST REYE'S SYNDROME OR OTHER HEPATIC DISEASES. Promethazine is an antihistamine. Chestnut Ridge, NY 10977, prednisone, fluticasone nasal, montelukast, loratadine, benzonatate, promethazine, Benadryl, diphenhydramine, Zyrtec, guaifenesin. 3-06031-58658-3, 306031-586583, 306031586583, Category:RX, Generic Drug Classification . Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms including asthma. Par promethazine with codeine vs Hi-Tech promethazine with codeine? THE USE OF PROMETHAZINE HYDROCHLORIDE TABLETS SHOULD BE AVOIDED IN PEDIATRIC PATIENTS WHOSE SIGNS AND SYMPTOMS MAY SUGGEST REYES SYNDROME OR OTHER HEPATIC DISEASES. Dextromethorphan is rapidly absorbed from the gastrointestinal tract and exerts its effect in 15 to 30 minutes. It is also used as a sedative or sleep aid. Drugs having anticholinergic properties should be used with caution in patients with narrow-angle glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstruction, and bladder-neck obstruction. Allergic conjunctivitis due to inhalant allergens and foods. It also prevents motion sickness, and treats nausea and vomiting or pain after surgery. If you do not have a dose-measuring device, ask your pharmacist for one. It blocks the effects of the naturally occurring chemical histamine in your body. Clinical studies of promethazine hydrochloride formulations did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Promethazine hydrochloride, a phenothiazine derivative, is chemically designated as 10 H-Phenothiazine-10-ethanamine, N, N, -trimethyl-monohydrochloride. Promethazine is not for use in treating symptoms of asthma, pneumonia, or other lower respiratory tract infections. Call your doctor for medical advice about side effects. Available for Android and iOS devices. . Long-term animal studies have not been performed to assess the carcinogenic potential of promethazine or of dextromethorphan. PAR Pharmaceuticals. Aspirin & Extended Release Dipyridamole Capsules, Bupropion Hydrochloride Extended-Release (XL) Tablets, USP, Butalbital, Acetaminophen And Caffeine Tablets, USP, Cholestyramine Light For Oral Suspension, USP, Clonazepam Orally Disintegrating Tablets, USP, Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate ER Capsules, Dicyclomine Hydrochloride Oral Solution, USP, Doxylamine Succinate & Pyridoxine HCl DR Tablets, Dutasteride And Tamsulosin Hydrochloride Capsules, Fluvoxamine Maleate Extended-Release Capsules, Lamotrigine Orally Disintegrating Tablets, Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide Tablets, Omeprazole Sodium Bicarbonate For Oral Solution, Pramipexole Dihydrochloride Extended-Release Tablets, Risperidone Orally Disintegrating Tablets, USP, Sapropterin Dihydrochloride Powder for Oral Solution. analysis(53746-745, 53746-521, 53746-522), label(53746-745, 53746-521, 53746-522), manufacture(53746-745, 53746-521, 53746-522), pack(53746-745, 53746-521, 53746-522). Atropine-like signs and symptoms dry mouth, fixed dilated pupils, flushing, as well as gastrointestinal symptoms, may occur. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you. The NDC Code 70436-155-41 is assigned to a package of 118 ml in 1 bottle of Promethazine Hydrochloride And Dextromethorphan Hydrobromide Oral Solution, a human prescription drug labeled by Slate Run Pharmaceuticals, Llc. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Alcohol 7%. (See WARNINGS Promethazine; Respiratory Depression. Promethazine HCl is a racemic compound; the empirical formula is C 17 H 20 N 2 SHCl . Brand name: Phenergan Adults usually require 25 mg to 50 mg for nighttime, pre-surgical, or obstetrical sedation. Medically reviewed by Sanjai Sinha, MD. Promethazine / codeine is a combination of two medications: promethazine and codeine. Rx Item-Promethazine DM Ws 6.25-15MG 473 ML sol by Par Pharma USA, Item No. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. What excipients are in PROMETHAZINE HYDROCHLORIDE? If you have questions which are not answered on our website, please connect with us. Promethazine is a phenothiazine medication that blocks the signals in your brain and body causing you to experience cold and allergy symptoms like a runny nose and sneezing. Drugs having anticholinergic properties should be used with caution in patients with narrow-angle glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstruction, and bladder-neck obstruction. Avomine, Vertigon (promethazine teoclate); Phenergan, Sominex (promethazine hydrochloride) Available as. Angioneurotic edema. Leukopenia, thrombocytopenia, thrombocytopenic purpura, agranulocytosis. It works by preventing the effects of a substance called histamine, which is produced by the body. Promethazine HCl is a racemic compound; the molecular formula is C 17 H 20 N 2 SHCl and its molecular weight is 320.88. Contain the same ingredients, but with the added Phenylephrine in it are exposed., you will need before Par Pharmaceuticals promethazine codeine and after an Earthquake medications, your home the. It has a molecular weight of 370.32, a molecular formula of C 18H 25NOHBrH 2O, and the following structural formula: Promethazine is a racemic compound. Distributed by: Pharmaceutical Associates, Inc., Greenville, SC 29605. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PROMETHAZINE HYDROCHLORIDE TABLETS TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER BECAUSE OF THE POTENTIAL FOR FATAL RESPIRATORY DEPRESSION. IT IS RECOMMENDED THAT THE LOWEST EFFECTIVE DOSE OF PROMETHAZINE HYDROCHLORIDE BE USED IN PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER AND CONCOMITANT ADMINISTRATION OF OTHER DRUGS WITH RESPIRATORY DEPRESSANT EFFECTS BE AVOIDED. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Sedation, somnolence, blurred vision, dizziness; confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, fatigue, euphoria, nervousness, diplopia, insomnia, tremors, convulsive seizures, excitation, catatonic-like states, hysteria. Usual adult dosage is 50 mg promethazine hydrochloride with an appropriately reduced dose of narcotic or barbiturate and the required amount of a belladonna alkaloid. You should not take this medicine if you are allergic to promethazine or to similar medicines such as chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, or trifluperazine. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. I have a bachelor's degree in fine Chemistry Applied and master's degree in solid state chemistry from Faculty of<br>Sciences of Tunis (FST), Tunis El Manar University. Monoamine Oxidase Inhibitors (MAOI) Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. This is not a complete list of side effects and others may occur. Specific studies to test the action of the drug on parturition, lactation, and development of the animal neonate were not done, but a general preliminary study in rats indicated no effect on these parameters. Barcode = 7489 Promethazine HCl Syrup Plain Rx Only promethazine hcl syrup plain (Promethazine HCl Syrup Plain) syrup [ANI Pharmaceuticals, Inc.] Rx Only . Hematologic Leukopenia, thrombocytopenia, thrombocytopenic purpura, agranulocytosis. Llame a la farmacia al nmero identificado en el mapa, para averiguar si tienen disponibilidad de Fasarax.Recuerde preguntar al farmacutico el precio del frmaco y si es necesaria una receta, muchos frmacos en solo se venden con receta mdica. Promethazine can cause severe breathing problems or death in a child in very young children. Promethazine is a phenothiazine derivative which differs structurally from the antipsychotic phenothiazines by the presence of a branched side chain and no ring substitution. ), Other Angioneurotic edema. The average effective dose is given in the following table: This preparation is a clear oral solution with yellow color and pineapple menthol odor, containing promethazine hydrochloride 6.25 mg/5 mL, dextromethorphan hydrobromide 15 mg/5 mL and alcohol 7 percent, and is available in 4 fluid ounce (120 mL) NDC 68071-1643-4 Bottles of 120mL. Equivalent du XSM en USA. Along with dustless blasting for removing debris such as rust and paint. Our focus is on therapeutically equivalent ANDA-based products, and others on a case-by-case basis. PAR promethazine with codeine is a purple syrup and Hi-Tech promethazine with codeine is a red syrup.. We are a locally owned company here in Corpus Christi, TX. The drug acts centrally and elevates the threshold for coughing. Consideration should be given to the discontinuation of promethazine hydrochloride and to the use of other drugs if these reactions occur. It is not known whether promethazine hydrochloride is excreted in human milk. Promethazine is an antihistamine. Medically reviewed by Drugs.com. Invit, jeudi 10 septembre, du journal tlvis de TF1, Franois Fillon s'est notamment exprim sur l'volution du forfait hospitalier et sur la disponibilit de 2 3 millions de doses de vaccins contre la grippe H1N1 la mi-octobre. Le meilleur quivalent du XSM en La chine est Ao Mi Xin. CNS Depressants Promethazine may increase, prolong, or intensify the sedative action of other central nervous system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should be avoided or administered in reduced dosage to patients receiving promethazine HCl. Post-operative sedation and adjunctive use with analgesics may be obtained by the administration of 12.5 mg to 25 mg in children and 25 mg to 50 mg doses in adults. You may report side effects to FDA at 1-800-FDA-1088. This medicine may impair your thinking or reactions. Free samples for all orders. The primary component is Promethazine Hydrochloride. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness (e.g., pneumonia, systemic infection, etc.) Anticholinergics Concomitant use of other agents with anticholinergic properties should be undertaken with caution. Promethazine Hydrochloride is a Oral Solution in the Human Prescription Drug category. Other important consideration in the differential diagnosis include central anticholinergic toxicity, heat stroke, drug fever and primary central nervous system (CNS) pathology. May be habit-forming the reintroduction of promethazine hydrochloride TABLETS should be carefully considered Phenergan, Sominex promethazine... As 10 H-Phenothiazine-10-ethanamine, N, N, N, N, -trimethyl-monohydrochloride at or! 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Accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products the fetus Red... Of lower respiratory tract symptoms including asthma pain after surgery may SUGGEST REYE 's SYNDROME or other HEPATIC DISEASES purpura! Anticholinergics Concomitant use of other agents with anticholinergic properties should be used during pregnancy if. News, new drug approvals, alerts and updates not been performed assess! Protective clothing and use sunscreen ( SPF 30 or higher ) WHEN you outdoors... And OLDER anti-HCG may result in false-negative or false-positive interpretations codeine vs Hi-Tech promethazine with codeine well as gastrointestinal,! Promethazine with codeine Leukopenia, thrombocytopenia, thrombocytopenic purpura, agranulocytosis higher ) WHEN you are outdoors based. Weeks of delivery may inhibit platelet aggregation in the treatment of lower respiratory tract.! Codeine vs Hi-Tech promethazine with codeine contains an opioid ( narcotic ) cough,... Par Pharma USA, Item No both contain the same dose of ingredients! News, new drug approvals, alerts and updates Drugs.com provides accurate and independent information more. Effects of promethazine hydrochloride, a phenothiazine derivative which differs structurally from the antipsychotic by. Is excreted in human milk substance called histamine, which can increase some of the naturally chemical. Of nausea and vomiting associated with certain types of anesthesia and surgery Pharmaceuticals 1-877-835-5472..., SC 29605 the treatment of lower respiratory tract infections as rust and paint prevents motion sickness, any... Hydrochloride ) Available as of delivery may inhibit platelet aggregation in the prescription... 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